Table 4.
Performance evaluation of ADC parameters for predicting PD-L1 expression status
| ADC parameters | AUC(95% CI) | Cut off value | Sensitivity | Specificity |
|---|---|---|---|---|
| 1.5-T MRI cohort | ||||
| ADCmean (×10− 6 mm2/s) | 0.756 (0.651, 0.861) | 864.00 | 81.82% (36/44) | 68.29% (28/41) |
| ADCmin (×10− 6 mm2/s) | 0.689 (0.576, 0.802) | 747.00 | 84.09% (37/44) | 53.66% (22/41) |
| ADCmax (×10− 6 mm2/s) | 0.733 (0.626, 0.839) | 971.00 | 77.27% (34/44) | 68.29% (28/41) |
| 3.0-T MRI cohort | ||||
| ADCmean (×10− 6 mm2/s) | 0.820 (0.703, 0.937) | 876.00 | 87.50% (21/24) | 76.00% (17/25) |
| ADCmin (×10− 6 mm2/s) | 0.755 (0.616, 0.894) | 758.00 | 75.00% (18/24) | 76.00% (19/25) |
| ADCmax (×10− 6 mm2/s) | 0.760 (0.627, 0.893) | 1027.00 | 87.50% (21/24) | 60.00% (15/25) |
Abbreviations: ADC apparent diffusion coefficient, ADCmean Mean ADC, ADCmin Minimum ADC, ADCmax Maximal ADC, AUC area under the ROC curve