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. 2023 Oct 13;23:389. doi: 10.1186/s12890-023-02696-x

Table 5.

Characteristics of patients with ABPA receiving omalizumab with and without AR.

All participants With AR Without AR P
Baseline Data
Blood eosinophil count, cells/µL 590 (270–840) 510 (190–910) 630 (580–930) 0.40
Total serum IgE level, kU/L 2627 ± 1904 2540 ± 2050 2846 ± 1736 1.00
Dose of corticosteroids, mg/d 2.5 (0.6–12) 2.5 (0.6–14) 4.5 (0.6–11) 0.89
ACT score 17 ± 5 16 ± 6 18 ± 4 0.67
FVC %pre 81 ± 13 80 ± 11 83 ± 15 0.48
FEV1%pre 69 ± 15 68 ± 15 71 ± 15 0.78
Acute exacerbation rate 2 (0.8–3.3) 1.5 (0.8–3.0) 3.5 (0.5–5.0) 0.32
Hospitalization rate 1 (0–1.3) 0.5 (0–1.0) 1.5 (0.3–4.3) 0.20
After treatment
Blood eosinophil count, cells/µL 180 (120–490) 240 (110–600) 106 (110–420) 0.62
Total serum IgE level, kU/L 1913 ± 1898 2384 ± 2040 737 ± 735 0.16
Dose of corticosteroids, mg/d 0.6 (0.5–4.2) 0 (0.5–4.2) 0.8 (0.1–6.3) 0.94
ACT score 22 ± 3 21 ± 3 23 ± 1 0.67
FVC %pre 86 ± 17 84 ± 15 89 ± 22 0.40
FEV1%pre 76 ± 18 77 ± 18 74 ± 21 0.67
Acute exacerbation rate 0 (0–1.0) 0 (0–1.3) 0 (0–0.8) 0.51
Hospitalization rate 0 (0–0) 0 (0–0.3) 0 (0–0) 0.35

ABPA, allergic bronchopulmonary aspergillosis; AR, allergic rhinitis; ACT, asthma control test;

FEV1, percentage of the forced expiratory volume in 1 s; FEV1%pre, forced expiratory volume in 1 s of predicted