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. 2023 Oct 9;15(19):4900. doi: 10.3390/cancers15194900

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overexpression of MBL2 inhibits HCC growth in vivo and its relationship with clinical cancer stage. (A) Nude mice were subcutaneously injected with Huh7 cells stably overexpressing MBL2. (B,C) The volumes and weights of the subcutaneous tumors showed that the overexpression of MBL2 inhibits subcutaneous tumor formation in nude mice. (D) The level of MBL2 was lower in liver cancer tissue compared to normal liver tissues (* p < 0.05, *** p < 0.001). MBL2, mannose-binding lectin 2; HCC, hepatocellular carcinoma; Huh7, human hepatoma-derived 7.