Figure 6.

MBL2 expression is associated with immune infiltration of HCC. (A) Protein–protein interaction network and functional annotation for MBL2. (B) TIMER 2.0 was employed to analyze the correlations between MBL2 expression and immune infiltration of cancer-associated fibroblasts, T-regulatory cells, natural killer cells, and tumor purity. (C) The ImmuCellAI platform was used to assess the correlations among MBL2 expression, immune-suppressive genes, and infiltration of diverse immune cells. (D,E) Correlation analyses were performed using the TIDE method to examine the relationships between MBL2 expression and various immune features. MBL2, mannose-binding lectin 2; HCC, hepatocellular carcinoma; TIDE, tumor immune dysfunction and exclusion.