FIG. 3.

Bactericidal activities of simulated concentrations achieved in the serum of humans following the administration of oral doses of amoxicillin-clavulanate at 500 plus 125 mg, respectively, twice daily (•), 500 mg of amoxicillin twice daily (○), 200 mg of cefpodoxime twice daily (⧫), and 250 mg of cefuroxime twice daily (□) against S. pneumoniae ATCC 6303. The growth of an untreated control culture (×) was used for comparison. Arrows represent the times at which the antibiotic doses were administered.