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. 2023 Sep 27;13(19):3033. doi: 10.3390/ani13193033

Table 5.

Response to vaccination and acute phase response of Nellore calves receiving saline solution (Saline; n = 14) or bovine-appeasing substance (BAS; n = 14) at weaning.

Items 1 Treatments SEM p-Value
Saline BAS Treatment Treatment × Day
Response to vaccination
  IBR
 Titers, log2 2.94 3.06 0.53 0.85 0.66
 Seroconversion, % total 91.7 100 5.87 0.33 0.33
  PI3
 Titers, log2 0.03 0.05
 d 0 0.00 0.00 0.53
 d 15 3.21 b 5.49 a 0.53
 d 51 4.82 b 6.15 a 0.53
 Seroconversion, % total 0.12 0.10
 d 0 0.00 0.00 0.09
 d 15 66.7 b 100 a 0.09
 d 51 100 100 0.09
  BVDV-1
 Titers, log2 0.10 0.02
 d 0 0.26 0.40 0.61
 d 15 0.26 0.57 0.61
 d 51 4.26 b 6.40 a 0.61
 Seroconversion, % total 66.7 100 12.0 0.09 0.69
  BVDV-2
 Titers, log2 1.06 1.28 0.42 0.72 0.87
 Seroconversion, % total 66.7 66.7 12.2 1.00 1.00
Acute phase response
  Haptoglobin, mg/mL 0.41 0.43 0.02 0.46 0.40
  Ceruloplasmin, mg/mL 15.7 14.8 0.64 0.36 0.41

1 On d 0, calves were vaccinated against infectious bovine rhinotracheitis, bovine viral diarrhea virus type 1 and 2 (BVDV-1 and 2), parainfluenza-3 (PI3) virus, bovine respiratory syncytial virus, and Mannheimia haemolytica (2 mL s.c.; Bovi Shield Gold One Shot, Zoetis). a,b Within a row, without a common superscript, differ (p ≤ 0.05) or tend to differ (p ≤ 0.10).