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. 2023 Sep 22;12(19):2332. doi: 10.3390/cells12192332

Figure 11.

Figure 11

Effect of JZL184 on hypoxia-induced HIF-1α and HIF-2α protein expression in A549 (A) or H358 cells (C) or in nuclear extracts of A549 cells (B). Under hypoxic conditions, A549 and H358 cells were incubated with vehicle or JZL184 for 6 h. Western blot images (A–C) are representative of each experiment. Percentage values given (A–C) refer to vehicle-treated hypoxic A549 or H358 cells, each set to 100%. Data represent mean ± SEM of n = 4 (A,B) or n = 3 (C). * p ≤ 0.05, *** p ≤ 0.001, **** p ≤ 0.0001 vs. vehicle-treated hypoxic cells; one-way ANOVA with Dunnett´s post hoc test.