Table 1.
General characteristics of all included patients.
| Characteristic | All Patients (n = 923) | Nonfunctioning AI (n = 647) | MACS (n = 276) | p |
|---|---|---|---|---|
| Age at diagnosis (years) | 62.4 ± 11.12 | 62.15 ± 11.04 | 64.12 ± 10.32 | 0.02 |
| Sex (%male/%female) | 53.6/46.4 | 52.9/47.1 | 55.3/44.7 | 0.28 |
| Adenoma size | 22.3 ± 3.5 | 20.3 ± 3.8 | 23.1 ± 2.0 | 0.57 |
| Tobacco exposure | ||||
| Active smoker (% and n) | 27.4 (52/190) | 24.6 (34/138) | 34.6 (18/52) | 0.28 |
| Former smoker (% and n) | 39.9 (215/552) | 40.1 (150/374) | 36.5 (65/178) | 0.11 |
| Complications | ||||
| Hypertension (% and n) | 54.7 (502/918) | 51.4 (331/644) | 62.4(171/274) | 0.001 |
| Diabetes (% and n) | 24.5 (224/913) | 23.3 (149/639) | 27.4 (75/274) | 0.11 |
| Dyslipidemia (% and n) | 48.2 (440/913) | 47.3 (303/640) | 50.2 (137/273) | 0.23 |
| Cardiovascular complications (% and n) | 2 (18/914) | 1.9 (12/640) | 2.2 (6/274) | 0.46 |
| Cerebrovascular complications (% and n) | 10.9 (99/910) | 10.2 (65/640) | 12.6 (34/270) | 0.16 |
| Obesity (% and n) | 40.5 (293/723) | 41.9 (209/499) | 37.5 (84/224) | 0.15 |
| Adenomas in other locations | 36 (298/827) | 32 (207/647) | 33 (91/276) | 0.41 |
| Location | ||||
| Pituitary (% and n) | 4.1 (38/935) | 1.1 (7/647) | 1.4 (4/276) | 0.42 |
| Thyroid (% and n) | 24.4 (229/935) | 25.2 (163/647) | 23.9 (66/276) | 0.38 |
| Parathyroid (% and n) | 4.3 (40/935) | 2.5 (16/647) | 2.5 (7/276) | 0.54 |
| Others (% and n) | 33.4 (297/889) | 31.8 (206/647) | 33 (91/276) | 0.38 |
| Mortality (% and n) | 2.2 (20/923) | 1.2 (8/647) | 4.3 (12/276) | 0.005 |
Legend: MACS: Mild autonomous cortisol secretion; AI: adrenal incidentaloma.