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. 2023 Sep 30;12(19):2388. doi: 10.3390/cells12192388

Figure 3.

Figure 3

Self-identification as Black or African-American was associated with enrichment in ribosome and MYC biology-related genes. A. Bar graph indicating numbers of up-regulated and down-regulated DEGs identified in non-cancer ipsilateral samples from women identifying as Black or African-American versus white. B. Bar graph presenting the top ten GO gene sets with the lowest significant FDR q-values identified from the MSigDB Collection utilizing identified DEGs in non-cancer ipsilateral samples from women identifying as Black or African-American versus white. C. Bar graph presenting three C2 gene sets with FDR q-values <0.05 identified from the MSigDB Collection utilizing identified DEGs in non-cancer ipsilateral samples from women identifying as Black or African-American versus white. D. Heat map illustrating relative expression levels of identified DEGs enriched in samples from individuals identifying as Black or African-American or white. DEGs enriched in Ribosome biology or MYC related are indicated. DEG: differentially expressed gene, at Padj ≤ 0.05. FDR: false discovery rate. MsigDB, Molecular Signatures Database, v7.5.1 [124,125,126] Color coding: Dark blue to yellow with increasing expression.