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. 2023 Sep 28;12(19):2374. doi: 10.3390/cells12192374

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Transcription of TLR2 in serum samples of SMA patients and healthy individuals. Transcription of TLR2 in serum samples of SMA patients and healthy individuals. (A) SMA patients (total) showed no alteration in TLR2 transcription compared to healthy control individuals (p > 0.05). (B) No difference was observed when comparing the samples of SMA patients at T0 and T1 (p > 0.05). (C) TLR2 transcription counts were unaffected in SMA R patients (p > 0.05). (D) Transcription counts of TLR2 were reduced in SMA nR patients (p < 0.05). (E) Reduction of TLR2 transcription was observed in SMA type 2 patients (p < 0.05). (F) In SMA type 3 patients, TLR2 transcription was not affected (p > 0.05). n = 10 control individuals, 29 SMA patients (total), 18 SMA responders (R), 11 SMA non-responders (nR). Statistics: * p < 0.05.