Figure 2.

The number of differentially expressed circulating miRNAs after hydrocortisone administration. Differentially expressed circulating miRNAs were summarized by the direction of changes in increase or decrease after hydrocortisone administration compared with time-matched controls. Fold-changes were calculated as log2 (after administration/time-matched control), indicating the significant changes of |log2 fold-change| ≥ 1 after hydrocortisone administration at each post-dose time point by small RNA-seq (adjusted p-value: padj < 0.05).