Figure 6.

Spinal serotonin levels in response to the administration of low and high doses of L-DOPA. L-DOPA injection is likely to affect moderately but significantly the spinal serotonergic system, the main effect being observed with the dose of 100 mg/kg at which the cervical and lumbar 5HIAA levels are increased. Forelimb/hindlimb differences in each pharmacological conditions are indicated by asterisks placed between the horizontal histograms. Asterisks placed at the extremity of the histograms highlight the statistical differences obtained between the pharmacological groups at the forelimb and hindlimb levels. 5HIAA: 5-Hydroxyindolactic acid.