Table 2.

Comparison of monoamines levels in the cervical and lumbar spinal cord between the group receiving L-DOPA at different doses. Statistical differences are indicated in bold together with the associated p-value. ↗ increase, ↘ decrease.

	L-DOPA				Dopamine
	Cervical		Lumbar		Cervical		Lumbar
Kruskal-Wallis test	p Value		p Value		p Value		p Value
	<0.0001		<0.0001		<0.0001		<0.0001
Dunn’s multiple comparisons		p Value		p Value		p Value		p Value
L-DOPA 25 vs. L-DOPA 100	↗	<0.0001	↗	<0.0001	↗	<0.0001	↗	<0.0001
L-DOPA 25 vs. L-DOPA 150	↗	<0.0001	↗	<0.0001	↗	<0.0001	↗	<0.0001
L-DOPA 100 vs. L-DOPA 150		0.1102		0.5045		0.6345		>0.9999
	DOPAC				Noradrenaline
	Cervical		Lumbar		Cervical		Lumbar
Kruskal-Wallis test	p Value		p Value		p Value		p Value
	<0.0001		<0.0001		0.0005		0.2799
Dunn’s multiple comparisons		p Value		p Value		p Value		p Value
L-DOPA 25 vs. L-DOPA 100	↗	<0.0001	↗	<0.0001		0.2692
L-DOPA 25 vs. L-DOPA 150	↗	<0.0001	↗	<0.0001		0.0601
L-DOPA 100 vs. L-DOPA 150	↗	0.0280		0.1103	↗	0.0003
	5-HT				5-HIAA
	Cervical		Lumbar		Cervical		Lumbar
Kruskal-Wallis test	p Value		p Value		p Value		p Value
	0.0030		0.0001		<0.0001		<0.0001
Dunn’s multiple comparisons		p Value		p Value		p Value		p Value
L-DOPA 25 vs. L-DOPA 100		0.1278		0.3816	↗	<0.0001	↗	<0.0001
L-DOPA 25 vs. L-DOPA 150		0.4286	↘	0.0151		>0.9999		>0.9999
L-DOPA 100 vs. L-DOPA 150	↘	0.0029	↘	<0.0001	↘	0.0052	↘	0.0018