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. 2023 Sep 29;24(19):14741. doi: 10.3390/ijms241914741

Figure 2.

Figure 2

Photoisomerization mechanisms and cofactors of photoswitchable proteins. (A) The main mechanisms of photoisomerization. OFB mechanism produces a trans-S-trans conformation, meanwhile HT produces a trans-S-cis conformation. (B). Examples of the main photoswitching protein families found in fungi and bacteria; left, an example of LOV domain protein (PDB: 2PR5) with a flavin chromophore; center, an example of BhpP (PDB: 4O8G) with a biliverdin chromophore; right, an example of BLUF domain protein (PDB: 1YRX) with the flavin chromophore. Partially created with BioRender.com.