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Chemical structures of the four most common detergents used for membrane protein extraction step of the membrane protein structures solved using cryo-EM single-particle analysis in the last two years (2021–2022) available in the Protein Data Bank. (A) n-Dodecyl-β-D-maltopyranoside (DDM); (B) Lauryl maltose neopentyl glycol (LMNG); (C) Digitonin; (D) Glyco-diosgenin (GDN).
