Table 3. Significant gene set enrichment analysis (GSEA) results of HtrAs, including hallmark pathways.

ID	SetSize	EnrichmentScore	NES	pvalue	p.adjust	qvalue
KEGG_OXIDATIVE _PHOSPHORYLATION	24	0.6949955	2.026471	0.0001	0.0104	0.0086
REACTOME_THE_CITRIC_ACID_TCA _CYCLE_AND_RESPIRATORY _ELECTRON_TRANSPORT	29	0.6593472	2.004267	7.2e−05	0.0104	0.0086
REACTOME_RESPIRATORY _ELECTRON_TRANSPORT	28	0.6501578	1.962995	0.0002	0.0104	0.0086
REACTOME_RESPIRATORY_ELECTRON _TRANSPORT_ATP_SYNTHESIS _BY_CHEMIOSMOTIC_COUPLING _AND_HEAT_PRODUCTION _BY_UNCOUPLING_PROTEINS	28	0.6501578	1.962995	0.0002	0.0104	0.0086
KEGG_CARDIAC_MUSCLE _CONTRACTION	21	0.6910468	1.922093	0.0005	0.0251	0.0208
WP_HOSTPATHOGEN_INTERACTION _OF_HUMAN_CORONAVIRUSES _APOPTOSIS	13	−0.7185709	−1.972958	0.0016	0.0348	0.0288
WP_FAS_LIGAND_PATHWAY_AND _STRESS_INDUCTION _OF_HEAT_SHOCK_PROTEINS	17	−0.6576734	−1.968384	0.0016	0.0348	0.0288
KEGG_RIG_I_LIKE_RECEPTOR _SIGNALING_PATHWAY	15	−0.6774612	−1.952287	0.0016	0.0348	0.0288
WP_NOVEL_INTRACELLULAR _COMPONENTS_OF_RIGILIKE _RECEPTOR_PATHWAY	15	−0.6774612	−1.952287	0.0016	0.0348	0.0288
KEGG_TOLL_LIKE_RECEPTOR _SIGNALING_PATHWAY	20	−0.6209131	−1.945614	0.0019	0.0348	0.0288