TABLE 1.
Organism | Antibiotic | MIC (μg/ml) | Multiple of MIC | PAE (h) |
---|---|---|---|---|
E. coli ATCC 25922 | Ampicillin | 2.0 | 2 | −0.3 |
4 | −0.4 | |||
8 | −0.3 | |||
Ceftriaxone | 0.03 | 2 | −0.3 | |
4 | −0.2 | |||
8 | −0.5 | |||
Gentamicin | 1.0 | 1 | 0.7 | |
2 | 0.6 | |||
Ciprofloxacin | 0.015 | 1 | 1.5 | |
2 | 2.7 | |||
Rifampin | 16 | 1 | 0.6 | |
2 | 1.5 | |||
P. aeruginosa ATCC 27853 | Imipenem | 2.0 | 2 | 1.3 |
4 | 1.9 | |||
8 | 2.6 | |||
Ciprofloxacin | 0.5 | 2 | 0.7 |