Table 3.

Compiled list of potential candidates based on multivariate analysis and correlation. The table includes the results of the multivariate analysis, grouping candidates into four categories based on their beta coefficients for the corresponding response variables, D-dimers and IL-6. A positive beta coefficient greater than 0.1 is indicated by “+”, while a negative beta coefficient less than -0.1 is indicated by “−“. Proteins discussed in the Section 4 are highlighted in bold.

Group	Candidates
D-Dimer
D-Dimer +	TGFA, CD5, MMP2, MMP10, IL2RB, P-selectin, E-selectin, TNR5, TNR3, CXCL5, CCL23, Galectin, GPVI, TN13B
D-Dimer −	IL1α, IBP1, FABP4, UFO, CCL16, TPA, LDLR, TFR1, IL6RA, IL8, CBPB1, NTF3, IL2, CCL20, Chemerin, M-CSF, HGF, MMP9
IL-6
IL-6 +	IL4, FGF5, PPA5, TFF3, IBP7, ARTN, IL1α, IBP1, FABP4, UFO
Il-6 −	TNF14, UROK, PDGFA, VWF, CXCL1, EPCAM, PRTN3, IL13, NRTN, FGF23, M-CSF, HGF, MMP9

Abbreviations: ARTN (Artemin), CBPB1 (Carboxypeptidase B1), CCL (CC-chemokine ligand), CD (Cluster of differentiation), CXCL (C-X-C motif chemokine), EPCAM (epithelial cell adhesion molecule), FABP4 (fatty acid binding protein 4), FGF (fibroblast growth factor), GPVI (Glykoprotein 6), HGF (hepatocyte growth factor), IBP (Insulin-like Growth Factor-binding Protein), IL (Interleukin), IL2RB (interleukin 2 receptor subunit beta), IL6RA (interleukin 6 receptor, alpha), LDLR (low density lipoprotein receptor), M-CSF (macrophage colony-stimulating factor), MMP (matrix metalloproteinase), NRTN (Neurturin), NTF3 (Neutrophin 3), PDGFA (Platelet-derived growth factor A), PPA5 (Soluble inorganic pyrophosphatase 5), PRTN3 (Proteinase 3), TFF3 (Trefoil factor 3), TFR1 (Transferrin receptor 1), TGFA (Transforming growth factor alpha), TNF (Tumor necrosis factor), TN13B (TNF Superfamily Member 13b), TNR (Thiamine pyrophosphokinase), TPA (Plasminogen activator, tissue type), UFO (tyrosine-protein kinase receptor), UROK (Urokinase-type plasminogen activator), VWF (von Willebrand factor).