Table 1.
Baseline characteristics of the total study cohort after stratification according to CERT categories.
| Total Cohort (n = 379) |
Category 1 (Low Risk, n = 116) |
Category 2 (Moderate Risk, n = 140) |
Category 3 (High Risk, n = 77) |
Category 4 (Very High Risk, n = 46) |
p-Value | |
|---|---|---|---|---|---|---|
| Age, years | 67 [60–74] | 65 [57–74] | 67 [60–74] | 70 [64–75] | 71 [62–76] | 0.007 |
| Male sex, % (n) | 72 (273) | 73 (85) | 75 (105) | 73 (56) | 59 (27) | 0.127 |
| Current smokers, % (n) | 31 (89) | 34 (24) | 29 (32) | 30 (20) | 33 (13) | 0.793 |
| Ever smokers, % (n) | 84 (317) | 82 (95) | 85 (119) | 84 (65) | 83 (38) | 0.815 |
| Body mass index, kg/m2 | 26 [24–30] | 26 [24–30] | 26 [24–30] | 27 [24–30] | 26 [23–31] | 0.670 |
| Creatinine, mg/dL | 0.90 [0.77–1.05] |
0.90 [0.79–1.00] |
0.87 [0.77–1.00] |
0.90 [0.70–1.15] |
0.95 [0.72–1.26] |
0.166 |
| Hypertension, % (n) | 94 (356) | 93 (108) | 97 (136) | 88 (68) | 96 (44) | 0.698 |
| T2DM, % (n) | 40 (150) | 38 (44) | 34 (47) | 43 (33) | 57 (26) | 0.033 |
| CKD % (n) | 20 (75) | 16 (18) | 15 (21) | 25 (19) | 37 (17) | 0.001 |
| LDL-cholesterol, mg/dL | 102 [81–125] | 96 [83–119] | 105 [81–126] | 111 [79–149] | 92 [76–114] | 0.716 |
| Statin use at baseline, % (n) | 70 (266) | 78 (91) | 66 (92) | 62 (48) | 76 (35) | 0.247 |
| Rutherford score | 2 [1–3] | 2 [1–3] | 1 [0–3] | 3 [1–3] | 3 [1–4] | 0.006 |
| Ankle–brachial index | 1.0 [0.8–1.2] | 1.0 [0.9–1.2] | 1.0 [0.9–1.2] | 1.0 [0.8–1.1] | 0.9 [0.7–1.1] | 0.047 |