Table 2.
Comparison of clinical and endovascular findings according to preprocedural D-dimer levels.
| Tertile 1 284.0 ng/mL [216.5; 392.0] (n = 72) |
Tertile 2 761.5 ng/mL [615.2; 1022.2] (n = 72) |
Tertile 3 3285.0 ng/mL [2594.0; 7206.0] (n = 71) |
p-Value * | |
|---|---|---|---|---|
| Demographics and stroke risk factors | ||||
| Age (years) | 68.0 (±13.8) | 73.7 (±11.8) | 72.0 (±12.4) | 0.058 |
| Men | 46 (63.9) | 39 (54.2) | 28 (39.4) | 0.004 |
| Hypertension | 52 (72.2) | 52 (72.2) | 54 (76.1) | 0.605 |
| Diabetes | 23 (31.9) | 22 (30.6) | 26 (36.6) | 0.555 |
| Dyslipidemia | 24 (33.3) | 17 (23.6) | 13 (18.3) | 0.039 |
| Current smoking | 14 (19.4) | 10 (13.9) | 7 (9.9) | 0.103 |
| Coronary artery occlusive disease | 9 (12.5) | 14 (19.4) | 7 (9.9) | 0.654 |
| Atrial fibrillation | 29 (40.3) | 45 (62.5) | 38 (53.5) | 0.112 |
| Clinical conditions | ||||
| Initial NIHSS score | 10.5 [6.0; 16.0] | 15.0 [9.8; 19.2] | 15.0 [12.0; 19.5] | <0.001 |
| Intravenous tPA administration | 10 (13.9) | 31 (43.1) | 27 (38.0) | 0.002 |
| Location of occlusions | 0.589 | |||
| Internal carotid artery | 18 (25.0) | 30 (41.7) | 24 (33.8) | |
| Middle cerebral artery | 44 (61.1) | 35 (48.6) | 38 (53.5) | |
| Vertebral artery | 9 (12.5) | 6 (8.3) | 8 (11.3) | |
| Basilar artery | 1 (1.4) | 1 (1.4) | 1 (1.4) | |
| Onset-to-puncture time (minutes) | 531.0 [266.0; 908.0] | 308.0 [166.0; 657.0] | 265.0 [160.0; 650.0] | 0.007 |
| Use of balloon guide catheter | 59 (81.9) | 64 (88.9) | 60 (84.5) | 0.664 |
| Endovascular outcomes | ||||
| Successful recanalization | 67 (93.1) | 70 (97.2) | 66 (93.0) | 0.984 |
| Puncture-to-recanalization time (minutes) | 28.0 [18.0; 48.0] | 30.0 [24.0; 54.0] | 37.5 [23.2; 61.2] | 0.044 |
| Complete recanalization | 46 (63.9) | 51 (70.8) | 41 (57.7) | 0.448 |
| First-pass recanalization | ||||
| Modified first-pass effect | 35 (48.6) | 35 (48.6) | 20 (28.2) | 0.014 |
| First-pass effect | 30 (41.7) | 26 (36.1) | 15 (21.1) | 0.009 |
| Thrombus fragmentation | 23 (31.9) | 24 (33.3) | 32 (45.1) | 0.105 |
| Number of passes of thrombectomy device | 1.8 (±1.4) | 2.0 (±1.4) | 2.7 (±1.5) | 0.002 |
| Favorable outcome | 42 (58.3) | 33 (45.8) | 12 (16.9) | <0.001 |
Values represent the mean and standard deviation (±), median with the first and third quartiles [in brackets], or the number of patients (in %); * p-value for trend. NIHSS, National Institutes of Health Stroke Scale; tPA, tissue-type plasminogen activator.