TABLE 1.

Quantitation of resistance to QD, MQ, QN, and CQ

Yeast clone	Fold resistancea
	QD	MQ	QN	CQ
Clone 2b	6.5 ± 1.0	5.6 ± 0.8	2.5 ± 0.5	5.6 ± 3.8
STI1c	7.0 ± 0.4d	3.4 ± 0.5e	2.0 ± 0.8f	2.7 ± 1.7f
Anti-STI1c	1.0 ± 0.1	1.3 ± 0.6	1.3 ± 0.6	1.3 ± 0.6
CIN5c	3.9 ± 0.5d	9.6 ± 1.4d	1.2 ± 0.2f	5.4 ± 0.7d
Anti-CIN5c	1.0 ± 0.1	1.5 ± 0.5	1.0 ± 0.1	1.3 ± 0.5
Clone 3b	4.8 ± 1.3	1.5 ± 0.6	1.3 ± 0.5	2.7 ± 0.6
YOR273cc	4.3 ± 1.5g	1.0 ± 0.0f	1.4 ± 0.5f	1.3 ± 0.6f
Anti-YOR273cc	1.5 ± 0.5	1.0 ± 0.0	1.3 ± 0.6	1.5 ± 0.5
Clone 1b	2.5 ± 1.3	22.4 ± 12.4	1.6 ± 0.6	1.8 ± 1.3
YBR233wc	1.3 ± 0.6f	13.5 ± 3.6d	1.2 ± 0.3f	2.9 ± 1.7f
Anti-YBR233wc	1.2 ± 0.3	1.3 ± 0.6	1.2 ± 0.3	1.3 ± 0.6

^aSignificance of resistance for individual ORFs was assessed by comparison with drug resistance conferred by the same ORF cloned in the antisense orientation in the pVT-U expression vector. 

^bFold resistance over that of transformants containing insertless vector YEp24. 

^cFold resistance over that of transformants containing insertless vector pVT-U. 

^dP < 0.001. 

^eP < 0.01. 

^fNot significant. 

^gP < 0.05.