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. 2023 Sep 26;15(19):4149. doi: 10.3390/nu15194149

Figure 3.

Figure 3

Plausible mechanisms by which glucose-lowering drugs might impact on sarcopenia acting on sarcopenia. DPP-4i, dipeptidyl peptidase-4 inhibitors; GLP-1 Ras, glucagon-like peptide-1 receptor agonists; GLUT4, glucose transporter type 4; SGLT2i, sodium-glucose transport protein 2 inhibitors; and TZDs, thiazolidinediones. ↑, increase; ↓, decrease. Blue color and continue lines indicate a beneficial effect on sarcopenia; yellow color and dotted lines indicate a detrimental effect on sarcopenia [19]. Adapted from Massimino E et al., 2021 [19].