Table 3.
Outcomes of the EVT and No-EVT groups by CT-ASPECTS and DWI-ASPECTS strata
| Outcomes | CT-ASPECTS |
DWI-ASPECTS |
Interaction P | |||||
|---|---|---|---|---|---|---|---|---|
| EVT (n=53) | No-EVT (n=59) | OR (95% CI) | EVT (n=40) | No-EVT (n=31) | OR (95% CI) | |||
| Primary outcome | ||||||||
| One scale shift of mRS score toward 0 | NA | NA | Common OR | NA | NA | Common OR | 0.002 | |
| 1.29 (0.65–2.54) | 6.15 (2.46–16.3) | |||||||
| Secondary outcomes | ||||||||
| mRS score of 0–3 at 90 days | 10 (18.9) | 8 (13.6) | 1.48 (0.54–4.09) | 20 (50.0) | 4 (12.9) | 6.75 (1.99–22.8) | 0.06 | |
| mRS score of 0–2 at 90 days | 6 (11.3) | 4 (6.8) | 1.76 (0.47–6.60) | 8 (20.0) | 3 (9.7) | 2.33 (0.56–9.66) | 0.77 | |
| mRS score of 0–1 at 90 days | 3 (5.7) | 2 (3.4) | 1.71 (0.27–10.6) | 2 (5.0) | 1 (3.2) | 1.58 (0.14–18.3) | 0.96 | |
| NIHSS improvement of 8 points or more at 48 hours | 11 (20.8) | 7 (11.9) | 1.95 (0.69–5.46) | 20 (50.0) | 2 (6.5) | 14.5 (3.04–69.1) | 0.035 | |
| Safety outcomes | ||||||||
| Symptomatic intracranial hemorrhage within 48 hours | 6 (11.3) | 2 (3.4) | 3.64 (0.70–18.9) | 2 (5.0) | 1 (3.2) | 1.58 (0.14–18.3) | 0.58 | |
| Any intracranial hemorrhage within 48 hours | 30 (56.6) | 19 (32.2) | 2.75 (1.27–5.93) | 24 (60.0) | 10 (32.3) | 3.15 (1.18–8.42) | 0.83 | |
| Death within 90 days | 13 (24.5) | 8 (13.6) | 2.07 (0.78–5.48) | 4 (10.0) | 10 (32.3) | 0.23 (0.06–0.84) | 0.008 | |
| Recurrence of cerebral infarction within 90 days | 2 (3.8) | 5 (8.5) | 0.42 (0.08–2.28) | 2 (5.0) | 0 (0.0) | NA | NA | |
| Decompressive craniectomy within 7 days | 6 (11.3) | 6 (10.2) | 1.13 (0.34–3.74) | 1 (2.5) | 5 (16.1) | 0.13 (0.01–1.21) | 0.10 | |
Values are presented number (%) unless otherwise indicated.
EVT, endovascular therapy; OR, odds ratio; CI, confidence interval; ASPECTS, Alberta Stroke Program Early Computed Tomographic Score; CT-ASPECTS, ASPECTS based on non-contrast computed tomography; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; DWI-ASPECTS, ASPECTS based on diffusion-weighted magnetic resonance imaging; IQR, interquartile range; NA, not applicable.