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. 2023 Oct 9;15(19):4029. doi: 10.3390/polym15194029

Figure 10.

Figure 10

Comparison between biological skeletal muscle and electrospun PU structures. (A) Schematic of the hierarchical structure of skeletal muscle. (B) Mat of aligned nanofibers. eA single nanofiber corresponds to a myofibril (scale bar = 20 µm). (C) Bundle of aligned fibers, corresponding to a myofiber (scale bar = 100 µm). (D) Cross-section of an aligned bundle, showing the parallel arrangement of the inner nanofibers (scale bar = 100 µm). (E) Cross-section of the hierarchical nanofibrous electrospun structure (HNES), compared to the cross-section of a biological muscle belly (scale bar = 150 µm). (F) HNES membrane, resembling the epimysium membrane that envelops the muscle belly (scale bar = 100 µm). Reprinted with permission from [115].