Table 2. Meta-regression result of pooled possible risk factors of congenital anomalies in resource limited setting, 2022.

Authors	Effect	[95% Conf. Interval]	% Weight
Maternal illness
Jemal et al. [37]	6.10	2.39–15.57	35.23
Bekalu et al. [36]	4.30	1.65–11.37	64.77
Overall pooled	4.93	1.02–8.84	100.00
Unidentified drug use
Abebe et al. [39]	3.4	2.0–5.8	42.77
Feredegn et al. [33]	2.2	1.1–4.0	56.35
Bekalu et al. [36]	15.1	5.5–40.2	0.88
Overall pooled	2.83	1.19–4.46	100
Birth weight <2.5kg
Mekonnen et al. [30]	4.56	2.76–7.55	75.55
Gedamu et al. [31]	3.10	1.23–9.65	24.45
Overall pooled	4.20	2.12–6.28	100.00
Chat chewing
Bekalu et al. [36]	3.41	1.50–7.90	62.88
Jemal et al. [37]	4.76	1.57–14.47	15.48
Abebe et al. [39]	3.93	1.30–12.20	21.64
Overall pooled	3.73	1.20–6.30	100.00
Chemical exposure
Jemal et al. [37]	4.76	1.57–14.47	41.70
Abebe et al. [39]	3.93	1.26–12.17	58.30
Overall pooled	4.27	1.19–8.44	100.00
Never use folic acid
Jemal et al. [37]	0.57	0.41–0.73	25.00
Abebe et al. [39]	1.78	1.38–2.17	24.99
Bekalu et al. [36]	4.10	3.89–4.22	25.00
Gedamu et al. [31]	17.64	17.50–17.78	25.00
Overall pooled	6.01	2.87–14.89	100.00