Table 1.
Descriptive statistics on 304 boys participating in the Russian Children’s Study with prepubertal phthalate measurements
| n = 304 boys | |
|---|---|
|
| |
| Median Assessments [IQR] | 9 [8, 11] |
|
| |
| Baseline Demographics | |
|
| |
| Age at enrollment, mean (SD) | 8.23 (0.42) |
| WHO age-adjusted BMI z-score, mean (SD) | −0.36 (1.24) |
| Total calories consumed per day (kcal), median [IQR] | 2551 [2033, 3258] |
| Birthweight (kg), mean (SD) | 3.26 (0.52) |
| Duration of breast feeding (weeks), median [IQR] | 13 [4, 26] |
| Monthly family income ≤250 USD, n (%) | 184 (60.5) |
| Highest parental education, n (%) High school or less | 27 (9.0) |
| Some college or junior college | 184 (61.1) |
| College graduate | 90 (29.9) |
|
| |
| Prepubertal Phthalate Concentrations | Median [IQR] |
|
| |
| Diethyl (DEP) Metabolite, (ng/mL) | |
|
| |
| Monoethyl, MEP | 91.18 [51.38, 177.30] |
|
| |
| Di-n-butyl (DnBP) Metabolite, (ng/mL) | |
|
| |
| Mono-n-butyl, MnBP | 196.47 [125.38, 301.56] |
|
| |
| Diisobutyl (DiBP) Metabolite, (ng/mL) | |
|
| |
| Mono-isobutyl, MiBP | 57.07 [34.33, 87.66] |
|
| |
| Butyl Benzyl (BBzP) Metabolite, (ng/mL) | |
|
| |
| Monobenzyl, MBzP | 6.19 [2.89, 15.15] |
|
| |
| Di(2-ethylhexyl) (DEHP) Metabolites, (ng/mL) | |
|
| |
| Mono-(2-ethylhexyl), MEHP | 13.21 [7.23, 23.02] |
| Mono-(2-ethyl-5-hydroxyhexyl), MEHHP | 79.12 [51.00, 121.34] |
| Mono-(2-ethyl-5-oxohexyl), MEOHP | 65.83 [41.67, 105.30] |
| Mono-(2-ethyl-5-carboxypentyl), MCEPP | 159.44 [104.85, 260.10] |
|
| |
| Di-iso-nonylphthalate (DiNP) Metabolites, (ng/mL) | |
|
| |
| Mono-hydroxyisononyl, MHiNP | 8.21 [4.93, 14.81] |
| Mono-oxo-isononyl, MOiNP | 2.90 [1.73, 5.88] |
| Mono-carboxy-isononyl, MCOP | 6.41 [3.28, 11.86] |
|
| |
| Diisodecyl (DiDP) Metabolites, (ng/mL) | |
|
| |
| Mono-hydroxy-isodecyl, MHiDP | 4.09 [2.09, 8.24] |
| Mono-oxo-isodecyl, MOiDP | 0.55 [0.30, 0.91] |
| Mono-carboxy-isodecyl, MCNP | 0.80 [0.52, 1.39] |
|
| |
| Other Metabolite, (ng/mL) | |
|
| |
| Mono-(3-carboxypropyl), MCPP | 11.02 [6.56, 18.89] |
|
| |
| Molar Sums, (μmol/L) | |
|
| |
| DEHP Metabolites, ΣDEHP | 1.08 [0.71, 1.75] |
| DiNP Metabolites, ΣDiNP | 0.06 [0.03, 0.10] |
| DiDP Metabolites, ΣDiDP | 0.02 [0.01, 0.03] |
| Anti-androgenic phthalates, ΣAA | 2.49 [1.59, 3.60] |
Means and standard deviations are shown for normally distributed variables. Medians and IQRs are shown for nonnormally distributed variables. SD: Standard Deviation; WHO: World Health Organization; BMI: Body Mass Index; IQR: Interquartile Range; kg: kilograms; ng/mL: Nanograms per milliliter; μmol/L: micromole per liter; Data for some characteristics were not available for all boys: Total calories consumed per day (0.7%), Birthweight (0.3%), Duration of breast feeding (1.6%), and Highest parental education (1%); percentages are calculated based on those with available data.