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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: FASEB J. 2023 Nov;37(11):e23251. doi: 10.1096/fj.202301122RR

Figure 7. Global suppression of Lpcat3 ameliorates obesity and insulin resistance in ob/ob mice.

Figure 7.

A. Growth curve of ob/ob mice injected with Con-ASO or Lpcat3-ASO (n=8/group).

B-D. Body weight (B), eWAT weight (C) and sWAT weight (D) of ob/ob mice injected with Con-ASO or Lpcat3-ASO.

E. Daily food consumption of ob/ob mice injected with Con-ASO or Lpcat3-ASO.

F-K. GTT, ITT and area under the curve (AUC) analysis in ob/ob mice injected with Con-ASO or Lpcat3-ASO (n=5–8/group).

L-N. Fasting blood glucose (L), serum insulin levels (M) and HOMA-IR (N) of ob/ob mice injected with Con-ASO or Lpcat3-ASO.

Data are presented as means ± SEM. Statistical analysis was performed with Student’s t test (A-F, H-I, K-N), and two-way ANOVA (G and J). *P < 0.05, **P < 0.01.