Fig. 4. Experimental utility of CAP-Mac for interrogation of the newborn rhesus macaque brain.
a–f, CAP-Mac packaging three fluorescent reporters (a) to generate Brainbow-like labelling in rhesus macaque cerebellum (b), cortex (c) and thalamus (lateral geniculate nucleus) (d), enabling morphological reconstruction of neurons (e and f). g–i, Non-invasive delivery of ssCAG-GCaMP8s using CAP-Mac (g) for ex vivo two-photon imaging (h) and brain-wide GCaMP expression (i).