Table 2.
Intraclass correlation coefficient of QAF8 measurements.
| Disease stage | Intraclass correlation coefficient (ICC [95% CI]) | |
|---|---|---|
| Intra-day | Inter-day | |
| All eyes | 0.95 [0.93–0.96] | 0.79 [0.72–0.85] |
| Healthy | 0.91 [0.86–0.95] | 0.70 [0.54–0.83] |
| Early AMD | 0.96 [0.48–1.00] | N/A |
| Intermediate AMD | 0.95 [0.92–0.97] | 0.84 [0.73–0.91] |
| Late AMD (geographic atrophy and neovascular pooled) | 0.94 [0.90–0.97] | 0.64 [0.42–0.82] |
Listed are the intraclass correlation coefficient (ICC) of QAF8 measurements for two clinically relevant scenarios: “Intra-day” were duplicate images acquired on the same day: “Inter-day” were images acquired approximately 2 weeks apart. Row: 1 shows ICC for all eyes, 2 for healthy only, 3 for early-only, 4 for intermediate-only and 5 for late-AMD (both GA and neovascular pooled) only.