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. 2023 Oct 13;9:375. doi: 10.1038/s41420-023-01672-y

Fig. 1. Combination of PL with HSP90 inhibitors suppressed cell proliferation.

Fig. 1

AF Cell viability in HCT116, RKO, or HCT15 cells treated with the indicated concentration of 17-AAG or combined with PL for 24 h. GL Cell viability in HCT116, RKO, or HCT15 cells treated with the indicated concentration of ganetespib or combined with PL for 24 h. CI values were calculated using CompuSyn software. M, N Colony-forming ability of HCT116, RKO, or HCT15 cells. The concentration of 17-AAG on HCT116, RKO, and HCT15 cells was 0.0625 μM, 0.03125 μM and 1.25 μM, respectively, and the concentration of PL was 1.25 μM all the same. (*p < 0.05, **p < 0.01).