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Cryo-EM structures of SV1 and SV2 of GIPR in complex with Gs. (A) Cryo-EM map (Left) and structural model (Right) of SV1 in complex with Gs. (B) Cryo-EM map (Left) and structural model (Right) of SV2 in complex with Gs. SV1 is shown in hot pink, SV2 in cornflower blue, Gαs in medium slate blue, Gβ subunit in light salmon, Gγ subunit in olive, and Nb35 in medium purple.
