Table 3.

Optimization conditions of Sonogashira reaction.

Entry	Nanocatalyst (mg)	Temperature (°C)	Solvent	base	Time (min)	Yield (%)
1	10	50	H2O	K2CO3	15	70
2	20	50	H2O	K2CO3	15	95
3	30	50	H2O	K2CO3	15	95
4	20	25	H2O	K2CO3	15	35
5	10	100	H2O	K2CO3	15	80
6	20	50	EtOH	K2CO3	15	83
7	20	50	H2O	Na2CO3	15	15
8	20	50	H2O	Cs2CO3	15	85
9	20	50	H2O	NaOH	15	70
10	20	50	H2O	KOH	15	25

Reaction conditions. Aryl halide (1 mmol), Terminal alkyne (1.2 mmol), base (2 mmol), solvent (3 mL).