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. 2023 Oct 13;13:17346. doi: 10.1038/s41598-023-44660-z

Table 2.

Relationships between TPL2 and Pin1 expression with clinicopathological parameters in IDC.

n TPL2 Pin1
≥ 150 χ2 P  ≥ 150 χ2 P
Age
 < 50 years 31 19 (61.3%) 0.306 0.58 16 (51.6%) 0.235 0.628
 ≥ 50 years 49 33 (67.3%) 28 (57.1%)
Tumor size
 ≤ 2 cm 26 20 (76.9%) 2.407 0.121 16 (61.5%) 0.665 0.415
 > 2 cm 54 32 (59.3%) 28 (51.9%)
Histological grade
1–2 50 37 (74%) 4.747 0.029 30 (60%) 1.347 0.246
3 30 15 (50%) 14 (46.7%)
Lymph node metastasis
Yes 48 29 (60.4%) 1.108 0.293 24 (50%) 1.212 0.271
No 32 23 (71.9%) 20 (62.5%)
TNM stage
I 16 14 (87.5%) 4.451 0.035 11 (68.8%) 1.528 0.216
II–III 64 38 (59.4%) 33 (51.6%)
ER
 +  49 35 (71.4%) 2.297 0.13 32 (65.3%) 5.427 0.02
- 31 17 (54.8%) 12 (38.7%)
PR
 +  37 27 (73.0%) 1.923 0.165 24 (64.9%) 2.707 0.100
- 43 25 (58.1%) 20 (46.5%)

TPL2, tumor progression locus 2; Pin1, peptidyl-prolyl cis–trans isomerase 1; TNM, tumor-node-metastasis; ER, estrogen receptor; PR, progesterone receptor.

*Pearson’s chi-square test.

Significant are in value bold.