1 Mortality (all cause) |
1 |
95 |
Risk Ratio (M‐H, Random, 95% CI) |
0.73 [0.17, 3.11] |
2 Mortality (related to fungal infection) |
1 |
95 |
Risk Ratio (M‐H, Random, 95% CI) |
0.20 [0.01, 3.98] |
3 Complete resolution of fungal infection |
1 |
5 |
Risk Ratio (M‐H, Random, 95% CI) |
1.5 [0.18, 12.46] |
4 Partial resolution of fungal infection |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
5 Resolution of fever in suspected fungal infection |
2 |
297 |
Risk Ratio (M‐H, Random, 95% CI) |
1.23 [1.00, 1.52] |
6 Progression of disease requiring change / addition of an antifungal agent |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
7 Breakthrough fungal infection requiring change / addition of an antifungal agent |
3 |
345 |
Risk Ratio (M‐H, Random, 95% CI) |
0.67 [0.24, 1.84] |
8 Any clinically significant adverse reactions attributed to the antifungal agent resulting in discontinuation, dose reduction or change in therapy |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
9 Any clinically significant adverse reactions attributed to the antifungal agent (total) |
2 |
299 |
Risk Ratio (M‐H, Random, 95% CI) |
0.49 [0.21, 1.17] |
10 Nephrotoxicity |
4 |
371 |
Risk Ratio (M‐H, Random, 95% CI) |
0.43 [0.21, 0.90] |
11 Hypokalaemia |
3 |
345 |
Risk Ratio (M‐H, Random, 95% CI) |
0.71 [0.45, 1.14] |
12 Hepatotoxicity |
3 |
345 |
Risk Ratio (M‐H, Random, 95% CI) |
1.12 [0.74, 1.71] |
13 Infusion‐related reactions |
2 |
284 |
Risk Ratio (M‐H, Random, 95% CI) |
0.91 [0.59, 1.38] |
13.1 Fever ‐ Liposomal AmB vs. Conventional Amphotericin B |
1 |
96 |
Risk Ratio (M‐H, Random, 95% CI) |
0.98 [0.86, 1.11] |
13.2 Fever ‐ ABCD vs. Conventional Amphotericin B |
1 |
46 |
Risk Ratio (M‐H, Random, 95% CI) |
0.94 [0.69, 1.27] |
13.3 Chills ‐ Liposomal AmB vs. Conventional Amphotericin B |
1 |
96 |
Risk Ratio (M‐H, Random, 95% CI) |
0.37 [0.21, 0.64] |
13.4 Chills ‐ ABCD vs. Conventional Amphotericin B |
1 |
46 |
Risk Ratio (M‐H, Random, 95% CI) |
1.76 [1.09, 2.85] |
14 Haematological disturbances |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
15 Neurological disturbances |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
16 Gastrointesitnal toxicity |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
17 Length of Stay |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
18 Quality of Life |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
19 Cost |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |