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. 2023 Oct 11;11:e16268. doi: 10.7717/peerj.16268

Table 1. Baseline and procedural characteristics of included studies (Sweeney et al., 2003).

No Study Year Study design Type Country Intervention Sample size (n) The diagnosis of PCIM
1 Vijayaraman et al. (2019a) 2019 Single-arm Retrospective USA HBP 57 A 10% decrease in left ventricular ejection fraction (LVEF) from baseline resulting in LVEF <50% among patients experiencing >20% RV pacing without an alternative cause of cardiomyopathy.
2 Li et al. (2021) 2021 Single-arm Perspective China LBBP 10 The baseline of the left ventricular ejection fraction (LVEF) is no less than 50%, and the LVEF during follow-up is no more than 40%. The baseline of the LVEF is less than 50%, and the absolute value of the LVEF is reduced by more than 10% during follow-up. The total value of the LVEF is reduced by 10% regardless of the LVEF baseline.
3 Shan et al. (2018) 2018 Single-arm Perspective China HBP 11 Pacing at least 20% of the time despite device reprogramming to minimize ventricular pacing
4 Qian et al. (2021) 2021 Control-conhort Perspective China LBBP 13 A ≥10% decrease in left ventricular ejection fraction (LVEF) after RV pacing (ventricular pacing percentage over 20%) with resultant LVEF ≤50% without an alternative cause of cardiomyopathy, and with symptoms of heart failure.
5 Yang et al. (2021) 2021 Single-arm Perspective China HBP and LBBP 34 (29/5) (1) Patients with prior RVP implantation (including DDD and VVI pacemaker.) and the percentage of RVP > 40%; (2) A LVEF of ≤40% caused by a new onset LVEF decrease of >10% from baseline, without other identifiable causes.
6 Ye et al. (2021) 2021 Single-arm Retrospective China LBBP 19 (1) A >10% decrease in left ventricular ejection fraction (LVEF) after chronic RVP resulting in LVEF ≤ 50%. (2) The pacing percentage of RVP was >40%.
7 Rademakers et al. (2022) 2022 Single-arm Perspective The Netherlands LBBP 20 Patients with RV pacing (ventricular pacing percentage over 70%), the value of the LVEF is reduced by at least 10%, resulting in LVEF <50%.