Table 1.
The overlapped metabolites in the plasma of the two compared groups.
| HFD vs. Chow | HFD-exercise vs. HFD | ||||||
|---|---|---|---|---|---|---|---|
| Class | Metabolite | Ratio | P-value | VIP | Ratio | P-value | VIP |
| Amino acids | beta-Alanine | 0.4557 | 0.0025 | 1.3250 | 1.5075 | 0.0271 | 1.2331 |
| Isoleucine | 1.3932 | 0.0000 | 1.5600 | 0.6426 | 0.0000 | 1.7905 | |
| Leucine | 1.2506 | 0.0000 | 1.4852 | 0.6804 | 0.0000 | 1.8272 | |
| Ornithine | 2.2846 | 0.0016 | 1.4743 | 0.6012 | 0.0071 | 1.5746 | |
| Phenylalanine | 1.3051 | 0.0076 | 1.3500 | 0.7077 | 0.0031 | 1.7187 | |
| Proline | 1.2069 | 0.0329 | 1.0047 | 0.7594 | 0.0052 | 1.5130 | |
| Tryptophan | 1.2612 | 0.0010 | 1.3258 | 0.8199 | 0.0029 | 1.5238 | |
| Tyrosine | 1.3757 | 0.0014 | 1.4145 | 0.8336 | 0.0382 | 1.1529 | |
| Valine | 1.2446 | 0.0191 | 1.1402 | 0.7070 | 0.0031 | 1.6843 | |
| Carnitines | 2-Methylbutyroylcarnitine | 1.7471 | 0.0025 | 1.3540 | 0.5044 | 0.0043 | 1.6365 |
| Butyrylcarnitine | 2.0816 | 0.0021 | 1.4674 | 0.5108 | 0.0027 | 1.7050 | |
| Dodecanoylcarnitine | 1.2252 | 0.0420 | 1.1584 | 0.8962 | 0.0054 | 1.5206 | |
| Hexanylcarnitine | 1.7309 | 0.0013 | 1.3581 | 0.5757 | 0.0020 | 1.5720 | |
| Isovalerylcarnitine | 1.3826 | 0.0225 | 1.1726 | 0.5000 | 0.0043 | 1.7284 | |
| Oleylcarnitine | 3.1747 | 0.0000 | 1.6036 | 0.7809 | 0.0132 | 1.3646 | |
| Palmitoylcarnitine | 2.0608 | 0.0000 | 1.5910 | 0.7685 | 0.0014 | 1.6036 | |
| Stearylcarnitine | 7.5675 | 0.0057 | 1.6257 | 0.6301 | 0.0010 | 1.6300 | |
| Fatty acids | 2-Hydroxy-3-methylbutyric acid | 1.7840 | 0.0003 | 1.5583 | 0.6408 | 0.0005 | 1.7646 |
| 2-Methy-4-pentenoic acid | 1.4786 | 0.0029 | 1.2252 | 0.7610 | 0.0186 | 1.3151 | |
| 3-Methyladipic acid | 0.2011 | 0.0000 | 1.4802 | 2.1771 | 0.0310 | 1.2252 | |
| DHA | 0.5514 | 0.0177 | 1.2671 | 0.7666 | 0.0345 | 1.3044 | |
| Octanoic acid | 1.5618 | 0.0303 | 1.1514 | 0.8302 | 0.0494 | 1.2700 | |
| Organic acids | 3-Methyl-2-oxopentanoic acid | 2.3539 | 0.0000 | 1.5536 | 0.6199 | 0.0011 | 1.6243 |
| alpha-Ketoisovaleric acid | 1.4918 | 0.0000 | 1.5131 | 0.8751 | 0.0147 | 1.3524 | |
| Isocitric acid | 1.9926 | 0.0000 | 1.5718 | 0.6202 | 0.0000 | 1.8155 | |
| Ketoleucine | 2.3768 | 0.0002 | 1.5533 | 0.6502 | 0.0023 | 1.6459 | |
| Pyruvic acid | 1.2966 | 0.0433 | 1.0486 | 0.6369 | 0.0076 | 1.6239 | |
| Benzenoids | Ortho-hydroxyphenylacetic acid | 1.5429 | 0.0117 | 1.2708 | 0.5099 | 0.0031 | 1.5472 |
| Phenylpyruvic acid | 1.9453 | 0.0025 | 1.4361 | 0.4580 | 0.0043 | 1.7056 | |
| Bile acids | NorDCA | 0.4082 | 0.0228 | 1.0544 | 1.9048 | 0.0123 | 1.3438 |
| TCA | 38.9488 | 0.0025 | 1.2354 | 0.3591 | 0.0173 | 1.2352 | |
| TCDCA | 6.8307 | 0.0025 | 1.4305 | 0.4490 | 0.0043 | 1.5239 | |
| TDCA | 6.4974 | 0.0092 | 1.1176 | 0.4248 | 0.0173 | 1.0460 | |
| Indoles | Indole-3-pyruvic acid | 2.2016 | 0.0006 | 1.4607 | 0.5793 | 0.0030 | 1.6107 |
| Nucleotides | AMP | 0.1214 | 0.0101 | 1.0776 | 4.3713 | 0.0014 | 1.6108 |
| Peptides | Anserine | 0.5577 | 0.0025 | 1.4386 | 1.4815 | 0.0173 | 1.0606 |
| Glycylproline | 0.4289 | 0.0025 | 1.3857 | 1.2188 | 0.0469 | 1.1136 | |
| Phenylpropanoic acids | 2-Phenylpropionate | 0.0148 | 0.0025 | 1.2195 | 2.3611 | 0.0173 | 1.1474 |