Date	Event	Description
27 June 2012	Amended	Contact details updated.
24 September 2010	Amended	Contact details updated.
4 September 2009	Amended	This review is being updated by being split into smaller components. The first will be a review of the effectiveness of amitriptyline which is widely used to treat neuropathic pain.
20 August 2008	Amended	Converted to new review format.
19 August 2007	Amended	This update identified 13 new studies of which three were excluded (Aragona 2005; Beaumont 1980; Vidal 2004). One study awaiting assessment in the previous version is now included (Ciaramella 2000). The eleven new included studies reported on a total of 778 participants (Bowsher 1997; Ciaramella 2000; Forssell 2004; Lampl 2002; Mercadante 2002; Raja 2002; Reuben 2004; Robinson 2004; Rowbotham 2004; Sindrup 2003; Yucel 2004). Three of the new studies investigated antidepressant drugs as pre‐emptive treatments to prevent development of neuropathic pain (Bowsher 1997; Lampl 2002; Reuben 2004). We have added a table listing the studies with continuous data (Additional Table 01). This update has provided additional confirmation on the effectiveness of antidepressants for neuropathic pain and has provided new information on another antidepressant ‐ venlafaxine and previous readers of the review are advised to re‐read.