Schematic of a T. gondii tachyzoite highlighting the endolysosomal organelles, ELC and PLVAC and their connection with the secretory organelles (rhoptries, micronemes and dense granules). The inset shows an enlarged PLVAC with the known components. Some activities are shown with dashed lines as they have not been molecularly demonstrated. TgVP1, vacuolar proton pyrophosphatase; TgVATPase, vacuolar proton transport ATPase; NHE3, sodium proton exchanger; TgZnT, zinc transporter, TgCRT, chloroquine resistance transporter; TgPiT, phosphate sodium transporter; TgAQP1, aquaporin; TgA1, Ca²⁺-ATPase; Ca²⁺/H⁺, Ca²⁺ proton exchanger; TgCPL, cathepsin L; TgCPB, cathepsin B; TgCPC1, cathepsin C1; TgASP1, aspartic protease.