Table 4.

The association between childhood adversity and psychopathology is mediated via pathways through threat anticipation^a

	General psychopathology				Prodromal symptoms
					Anomalous experiences				Perceived distress
	aβ (CI)	p	Nmin	PM	aβ (CI)	p	Nmin	PM	aβ (CI)	p	Nmin	PM
Childhood trauma			1.239				563				563
Total effect	0.55 (0.49 – 0.61)	< 0.001			0.31 (0.23 – 0.42)	< 0.001			0.33 (0.25 – 0.43)	< 0.001
Direct effect	0.42 (0.35 – 0.49)	< 0.001			0.26 (0.17 – 0.36)	< 0.001			0.25 (0.16 – 0.36)	< 0.001
Indirect effect	0.13 (0.09 – 0.16)	< 0.001*		0.24	0.05 (0.01 – 0.09)	0.008*		0.16	0.08 (0.03 – 0.13)	< 0.001*		0.24
Bullying prevalence			1.045				449				449
Total effect	0.35 (0.29 – 0.41)	< 0.001			0.24 (0.15 – 0.32)	<0.001			0.20 (0.09 – 0.30)	< 0.001
Direct effect	0.30 (0.24 – 0.37)	< 0.001			0.20 (0.12 – 0.29)	< 0.001			0.20 (0.09 – 0.30)	< 0.001
Indirect effect	0.05 (0.03 – 0.07)	< 0.001*		0.14	0.04 (0.02 – 0.07)	0.001*		0.17	0.05 (0.03 – 0.09)	< 0.001*		0.25
Bullying severity			1.059				452				452
Total effect	0.41 (0.35 – 0.47)	< 0.001			0.27 (0.18 – 0.38)	<0.001			0.29 (0.20 – 0.40)	< 0.001
Direct effect	0.36 (0.31 – 0.43)	< 0.001			0.24 (0.14 – 0.34)	< .001			0.25 (0.15 – 0.36)	< 0.001
Indirect effect	0.05 (0.03 – 0.07)	< 0.001*		0.12	0.04 (0.02 – 0.07)	0.001*		0.15	0.05 (0.02 – 0.08)	< 0.001*		0.17

aβ = results adjusted for age, gender, self-reported ethnicity, and cognitive deviance. N_min = Due to varying numbers of missing values, different paths of the mediation analyses comprised varying sample sizes. Therefore, the minimum sample size is displayed here. P_M = proportion mediated

^aResults were bootstrapped with 1.000 repetitions

* = Statistically significant after Simes’ correction with n = 9