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Ten identified ELSI themes for genetic risk prediction for multifactorial disease, i.e., PGS, fall into three groups: potential benefits, potential risks and challenges, and ethical actions and obligations. ELSI specific to reproductive uses was also identified as a theme but is not reported in this manuscript. The four classic bioethics principles--beneficence, autonomy, justice and non-maleficence (Beauchamp and Childress 2013)--are represented with words in blue text
