Table 2.

Association between red blood cell proportions of C22:6n-3 (DHA) and C18:3n-3 (ALA) in tertiles and ANT scores on HRT-SE

Fatty acida	ANT HRT-SE, ms
	Minimally adjustedb				Fully adjustedc
	N	Coef	(95% CI)	P value	N	Coef	(95% CI)	P value
C22:6n-3
1st tertile (3.12)	106	Ref			76	Ref
2nd tertile (3.89)	104	– 18.53	( – 38.54; 1.48)	0.069	84	– 20.90	( – 43.98; 2.17)	0.076
3rd tertile (4.75)	106	– 21.12	( – 41.83; -0.41)	0.046	88	– 28.13	( – 52.30; -3.97)	0.023
Tertiles in continuousd	316	– 10.63	( – 20.98; -0.28)	0.044	248	– 13.94	( – 26.01; -1.88)	0.024
C18:3n-3
1st tertile (0.06)	104	Ref			85	Ref
2nd tertile (0.09)	103	5.89	( – 15.55; 27.33)	0.589	89	20.68	( – 3.26; 44.61)	0.090
3rd tertile (0.14)	109	6.84	( – 15.55; 29.23)	0.548	74	20.84	( – 4.10; 45.78)	0.101
Tertiles in continuousd	316	3.33	( – 7.83; 14.49)	0.557	248	10.08	( – 2.38; 22.53)	0.112

ANT attention network test, HRT hit reaction time, SE standard error, ms milliseconds, CI confidence interval, Ref reference group, Coef β coefficients estimated by linear regression models, N number of subjects with available data

Higher scores indicate worse attention performance

^aMedian of each fatty acid within tertile category

^bAdjusted for: school center, age and gender of the child

^cAdditionally adjusted for: body mass index of the child, alcohol consumption (have you ever consumed alcoholic beverages? yes/no), smoking habit (have you ever smoked a normal or electronic cigarette? yes/no), physical activity ≥ 3 times/week (yes/no), modified Mediterranean diet score (1–7 “low”/8–12 “high”), maternal educational level (university studies/lower education), paternal education level (university studies/lower education), maternal occupational social class (manual/non-manual) and paternal occupational social class (manual/non-manual)

^dThe p value is P for trend