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. 2022 Aug 12;32(11):2187–2195. doi: 10.1007/s00787-022-02064-w

Table 4.

Association between red blood cell proportions of C22:6n-3 (DHA) and C18:3n-3 (ALA) in tertiles and ANT scores on impulsivity index

Fatty acida Impulsivity index, ms
Minimally adjustedb Fully adjustedc
N Coef (95% CI) P value N Coef (95% CI) P value
C22:6n-3
1st tertile (3.12) 88 Ref 61 Ref
2nd tertile (3.89) 82 24.12 ( – 25.45; 73.69) 0.339 65 17.82 ( – 45.35; 80.98) 0.578
3rd tertile (4.75) 82 18.02 ( – 31.86; 67.90) 0.477 72 27.11 ( – 35.86; 90.07) 0.397
Tertiles in continuousd 252 9.15 ( – 15.76; 34.06) 0.470 198 13.42 ( – 17.93; 44.78) 0.399
C18:3n-3
1st tertile (0.06) 84 Ref 70 Ref
2nd tertile (0.09) 85 4.67 ( – 46.65; 55.99) 0.858 73 14.12 ( – 48.27; 76.51) 0.656
3rd tertile (0.14) 83  – 48.90 ( – 104.43; 6.63) 0.084 59  – 66.22 ( – 131.80;  – 0.65) 0.048
Tertiles in continuousd 252  – 24.86 ( – 52.67; 2.94) 0.079 198  – 34.19 ( – 67.16;  – 1.22) 0.042

ms milliseconds, CI confidence interval, Ref reference group, Coef. β coefficients estimated by linear regression models, N number of subjects with available data

Higher scores indicate worse attention performance (higher impulsivity)

aMedian of each fatty acid within tertile category

bAdjusted for: school center, age, and gender of the child

cAdditionally adjusted for: body mass index of the child, alcohol consumption (have you ever consumed alcoholic beverages? yes/no), smoking habit (have you ever smoked a normal or electronic cigarette? yes/no), physical activity ≥ 3 times/week (yes/no), modified Mediterranean diet score (1–7 “low”/8–12 “high”), maternal educational level (university studies/lower education), paternal education level (university studies/lower education), maternal occupational social class (manual/non-manual) and paternal occupational social class (manual/non-manual)

dThe p value is P for trend