Table 2.

Characteristics of included studies.

Study	Method of confirmation of dengue diagnosis	Country	Recruitment time	Clinical classification system	Number of patients	Included in meta-analysis? (yes/no)
Biswas, 201513	RT-PCR, viral isolation, IgM ELISA	Nicaragua	2005–2013	Both 1997 and 2009	789	Yes
Chaiyaratana, 200814	IgM, IgG ELISA	Thailand	2002–2005	1997	177	No
Conroy, 201515	IgM ELISA, viral isolation	Colombia	Not mentioned	1997	111	Yes
Cui, 201616	RT-PCR, NS1 detection	Singapore	Not mentioned	1997	116	Yes
Han, 201917	IgM, NS1 Elisa,	China	2016	1997	36	No
Hapugaswatta, 202118	NS1 rapid test	Sri Lanka	2015–17	2009	127	No
Houghton, 201019	RT-PCR	Colombia	2005–2006	1997	38	No
Koraka, 200420	IgM, IgG ELISA	Indonesia	1995–96	1997	32	No
Kularatnam, 201921	IgM ELISA	Sri Lanka	2013–14	1997	130	No
Kumar, 201222	RT-PCR	Singapore	2005–06	1997	58	Yes
Lam, 202023	RT-PCR, NS1 antigen, IgM assays	Vietnam	2013–15	2009	75	Yes
Laur, 199824	RT-PCR, IgM assay,	Tahiti	1996–97	1997	52	No
Liao, 201525	Antibody tests, virus isolation in C6/36 mosquito cells	China	2009	2009	51	No
Lin, 201926	NS1 Ag STRIP, RT-PCR, and serology	Taiwan	2014—2016	2009	108	Yes
Mapalagamage, 201827	IgM ELISA, rapid immunochromatography test (NS1)	Sri Lanka	2014–16	2009	138	No
Mapalagamage, 202028	IgM ELISA/rapid chromatographic detection NS1	Sri Lanka	2015–16	1997	80	Yes
Mariappan, 202129	NS1 ELISA, IgG, IgM ELISA	India	Not mentioned	2009	47	Yes
Nhi, 201630	serologic assays, virus isolation, RT-PCR	Vietnam	2011–12	2009	63	No
Pang, 201631	RT-PCR, IgM, IgG ELISA	Singapore	2005–08/2009–12	2009	158	No
Rathore, 202032	NS1 ELISA, RT-PCR	Sri Lanka	Not mentioned	1997	84	No
Saniathi, 202133	Not mentioned	Indonesia	2015–16	1997	80	Yes
Sigera, 201934	RT-PCR	Sri Lanka	2017–20	2009	32	Yes
Silva, 202135	NS1 antigen test,RT-qPCR	Sri Lanka	2018–19	2009	120	No
Suwarto, 201736	RT-PCR, IgG, IgM ELISA	Indonesia	2013–15	1997	103	Yes
van de Weg, 201437	RT-PCR, ELISA	Brazil	2011–12 Aruba/2010Brazil	2009	44	No
Villamor, 201738	NS1, RT-PCRIgM ELISA	Colombia	2003–09/2009–10	1997	345	Yes
Villamor, 201839	NS1, IgM ELISA, RT-PCR	Colombia	2003–09/2009–10	1997	344	No
Villar-Centeno, 200840	viral isolation, IgM assays	Colombia	Not mentioned	1997	201	Yes
Vuong, 202141	NS1 IgM ELISA, RT-PCR, viral isolation	Vietnam, El Salvador, Cambodia, Malaysia	2011–15	2009	281	Yes
Vuong, 202042	NS1 ELISA, RT-PCR	Vietnam, El Salvador, Cambodia, Malaysia	2011–15	2009	1117	Yes
Yacoub, 201743	NS1 ELISA, RT-PCR	Vietnam	2013–15	2009	293	No
Yacoub, 201644	RT-PCR, NS1 antigen or DENV IgM, IgG assays	Vietnam	2013–14	2009	132	Yes
Yamanaka, 201345	RT-PCR-NS1, IgM, IgG ELISA	Indonesia	2008–10	1997	130	Yes
Zain, 201746	IgM IgG ELISA for serotyping only	Indonesia	Not mentioned	2009	42	No
Chandrashekhar, 201947	IgG, IgM ELISA, NS1	India	2016–2018	2009	77	No
Fernando, 201648	IgG, IgM, NS1 ELISA,	Sri Lanka	2015	2009	30	Yes
Low, 201849	NS1 ELISA, RT-PCR	Malaysia	2016–2017	2009	82	No