Table 6.
Multiple regression analysis to assess the independent association of BRS (as dependant variable) with metabolic, inflammation and calcification markers (as independent variables) in patients with hypertension in recessive model (GG population) and dominant model (GC + GG population).
| Independent Variable | GG (n = 44) | GC + GG (= 125) | ||||||
|---|---|---|---|---|---|---|---|---|
| Standardized regression coefficient β | 95% CI | P value | Standardized regression coefficient β | 95% CI | P value | |||
| UL | LL | UL | LL | |||||
| BMI | 0.085 | − 0.144 | 0.279 | 0.520 | 0.094 | − 0.301 | 0.079 | 0.250 |
| RANKL/OPG | − 0.179 | − 23.216 | 4.646 | 0.185 | − 0.219 | − 22.327 | − 3.353 | 0.008 |
| TNF α | − 0.414 | − 0.177 | − 0.037 | 0.004 | − 0.367 | − 0.221 | − 0.084 | 0.000 |
| SDNN | 0.356 | 0.021 | 0.151 | 0.011 | 0.218 | 0.014 | 0.095 | 0.009 |
BRS: Baroreflex sensitivity; BMI: Body mass index; RANKL: Receptor activator of NfkB ligand OPG: Osteoprotegerin; TNF α: tumor necrosis factor alpha; SDNN: Standard deviation of normal-to-normal interval. The p value < 0.05 was considered significant.