Table 2.
Linkage of nonfunctional or weakly functional alleles of FUT1 to alleles of FUT2.
| Subject | Attribution | FUT1 | FUT2 | Deduced haplotype | Estimated phenotype |
|---|---|---|---|---|---|
| HG03919 | Bangladesh | Functional FUT1/FUT1*01N.09 | FUT2*0N.01/FUT2*01N.15 | FUT1*01N.09–FUT2*0N.01 | Bombay |
| HG04189 | Bangladesh | Functional FUT1/FUT1*01N.09 | FUT2*0N.01/FUT2*01N.02 | FUT1*01N.09–FUT2*0N.01 | Bombay |
| HG02733 | Pakistan | Functional FUT1/FUT1*01N.09 | Functional FUT2/FUT2*01N.02 | FUT1*01N.09–Functional FUT2 or FUT1*01N.09 FUT2*01N.02 | Para-Bombay or Bombay |
| Sinhalese | Sri Lanka | Functional FUT1/FUT1*01N.09 | Functional FUT2/FUT2*0N.01 | FUT1*01N.09–FUT2*0N.01 | Bombay |
| Tamil | Sri Lanka | Functional FUT1/FUT1*01N.09 | FUT2*0N.01/FUT2*0N.01 | FUT1*01N.09–FUT2*0N.01 | Bombay |
| Bangladeshi | Bangladesh | Functional FUT1/FUT1*01N.09 | FUT2*0N.01/FUT2*01N.15 | FUT1*01N.09–FUT2*0N.01 | Bombay |
| HG02789 | Pakistan | Functional FUT1/FUT1 with c.503C>G | FUT2*0N.01/FUT2*01N.02 | FUT1 with c.503C>G–FUT2*0N.01 or FUT1 with c.503C>G–FUT2*01N.02 | Bombay |
| NA21128 | Texas (Gujarati) | Functional FUT1/FUT1 with c.749G>C | FUT2*01N.02/ FUT2*01N.02 | FUT1 with c.749G>C–FUT2*01N.02 | Bombay |
| NA19095 | Nigerian | Functional FUT1/FUT1 with c.749T>C | Functional FUT2/ Functional FUT2 | FUT1 with c.749T>C–Functional FUT2 | Para-Bombay |
FUT1*01N.09: nonfunctional FUT1 alleles with c.725T>G missense substitution. FUT2*0N.01: approximately 10-kb deletion including the entire FUT2 coding region. FUT2*01N.15: nonfunctional FUT2 alleles with c.302C>T missense substitution. FUT2*01N.02: nonfunctional FUT2 alleles with 428G>A nonsense substitution. Estimated phenotype: estimated phenotype of homozygotes for each deduced haplotype.