Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structure of IMM47 and its mechanism of action for anti-tumor activities IMM47 binds to CD24 on the surface of tumor cells, promoting the activation of macrophages and NK cells through ADCP and ADCC and further activating the T cell immune response by the direct blocking of suppressive CD24/Siglec-10 interaction, as well as through macrophage antigen presentation and priming cytokines released by NK cells, inducing an all-around immune response.
