Unique stem cell lines identifier	Cell line 1: CHOPi008-A Cell line 2: CHOPi008-C
Alternative name(s) of stem cell lines	Cell line 1: TMD145.T21.G1S Cell line 2: DS145.T21.G1
Institution	Children’s Hospital of Philadelphia
Contact information of distributor	Stella T. Chou, MD chous@chop.edu
Type of cell lines	iPSC
Origin	Human
Additional origin info	Age: 8 days Sex: Male Ethnicity if known: White
Cell Source	Peripheral blood
Clonality	Clonal
Method of reprogramming	Sendai virus
Genetic Modification	Yes
Type of Genetic Modification	Spontaneous mutation/chromosomal abnormality (germline Trisomy 21 with and without somatic GATA1 mutation)
Evidence of the reprogramming transgene loss (including genomic copy if applicable)	qRT-PCR
Associated disease	Transient myeloproliferative disorder
Gene/locus	CHOPi008-A: GATA1 c.3_4insG (GATA1s) CHOPi008-C: GATA1
Date archived/stock date	August 2022
Cell line repository/bank	https://hpscreg.eu/cell-line/CHOPi008-A https://hpscreg.eu/cell-line/CHOPi008-C
Ethical approval	Children’s Hospital of Philadelphia, Committees for the Protection of Human Subjects (IRB), IRB 13-010038