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. 2023 Aug 7;6(3):107–110. doi: 10.1016/j.jimed.2023.07.005

Table 2.

The effects of combination treatment.

Combination Treatment Effects
IRE ​+ ​Anti-PD-1 - Enhanced tumor-specific CD8+ T cell response
- Increased recognition and presentation of tumor antigens by antigen-presenting cells
- Improved postoperative anti-tumor immune response
- Inhibition of tumor recurrence and metastasis
IRE ​+ ​Anti-OX40 - Enhanced killing effect of T cells on tumors
- Increased Ox40 receptor expression
- Strengthened postoperative anti-tumor immune response
- Inhibition of tumor recurrence and metastasis
IRE ​+ ​Anti-CTLA-4 - Increased tumor-specific CD8+ T cell response
- Presence of tumor-related memory-like T cells in tumor microenvironment
- Prevention of tumor progression and adverse events
- Enhanced tumor immune response