Table 5.
Treatment-Related Adverse Events
| Adverse Events | Any Grade n(%) | Grade 1–2 n(%) | Grade 3 n(%) | Grade 4 n(%) |
|---|---|---|---|---|
| Total | 35(85.3) | 28(68.3) | 7(17.0) | – |
| Fatigue | 10(24.4) | 8(19.5) | 2(4.9) | – |
| Decreased appetite | 10(24.4) | 7(17.1) | 3(7.3) | – |
| Fever | 13(31.7) | 12(29.3) | 1(2.4) | – |
| Nausea | 7(17.1) | 6(14.6) | 1(2.5) | – |
| Vomiting | 4(9.8) | 3(7.3) | 1(2.5) | – |
| Abdominal pain | 5(12.2) | 4(9.7) | 1(2.5) | – |
| Hand-foot syndrome | 6(14.8) | 4(9.8) | 1(2.5) | 1(2.5) |
| Diarrhea | 5(12.2) | 5(12.2) | – | – |
| Hypertension | 11(26.8) | 9(21.9) | 2(4.9) | – |
| Proteinuria | 5(12.2) | 3(7.2) | 1(2.5) | 1(2.5) |
| Skin rash | 7(17.1) | 5(12.1) | 1(2.5) | 1(2.5) |
| Thrombocytopenia | 6(14.6) | 6(14.6) | – | – |
| Hypothyroidism | 7(17.1) | 5(12.1) | 2(5.0) | – |
| Abnormal liver function | 26(63.4) | 21(51.2) | 4(9.7) | 1(2.5) |