Figure 3.

Representative pictures of achalasia subtypes and esophagogastric junction outflow obstruction (EGJOO) at high resolution manometry. In all conditions, the common manometric feature is the impaired relaxation of the esophago-gastric junction, as evaluated by a raised IRP. However, in achalasia peristalsis is never intact and it can be either absent (type I), with pan-esophageal pressurizations in at least 20% of wet swallows (type II) or with spastic/premature contractions (type III) in at least 20% of wet swallows (distal latency < 4.5 seconds), while EGJOO patients show normal/intact peristalsis.